Does the ClinPGx skill require an API key?

No, the ClinPGx REST API does not require authentication for basic access, though users should respect the rate limit of 2 requests per second.

What kind of genetic data can I retrieve with this skill?

You can access information on pharmacogenes (like CYP2D6 and CYP2C19), specific allele functions, population frequencies, and variants (rsIDs) associated with drug response.

Can this skill provide dosing recommendations?

Yes, it can retrieve evidence-based dosing recommendations from the Clinical Pharmacogenetics Implementation Consortium (CPIC) based on a patient's phenotype or genotype.

What is ClinPGx and how does it relate to PharmGKB?

ClinPGx is the clinical successor to the PharmGKB database, consolidating data from PharmGKB, CPIC, and PharmCAT to provide a unified resource for clinical pharmacogenomics.

ClinPGx Pharmacogenomics Database

Name: ClinPGx Pharmacogenomics Database
Author: ricable

byricable

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Data Science & ML

Accesses comprehensive pharmacogenomics data for precision medicine, genotype-guided dosing, and clinical decision support.

ClinPGx is a specialized skill for Claude Code that provides direct access to the successor of the PharmGKB database. It allows developers and researchers to programmatically query gene-drug interactions, CPIC guidelines, and allele function data essential for precision medicine. By integrating this skill, Claude can assist in analyzing how genetic variations affect medication response, interpret population allele frequencies, and retrieve regulatory drug labeling from the FDA and EMA to support evidence-based clinical dosing decisions.

Key Features

01Retrieve curated gene-drug pairs and clinical annotations with graded evidence levels.

02Search pharmacogenomic drug labels from global regulatory bodies like the FDA.

031 GitHub stars

04Query evidence-based CPIC clinical guidelines for genotype-guided dosing.

05Access allele function, phenotype assignment, and population frequency data.

06Explore pharmacokinetic and pharmacodynamic pathways for drug metabolism analysis.

Use Cases

01Building clinical decision support systems for personalized medicine applications.

02Conducting research on drug metabolism and potential adverse drug reactions (ADRs).

03Automating the interpretation of genetic test results for pharmacogenomic reporting.

What are Skills?·How to Install

Install with 🐟 Skill.Fish

npx skillfish add ricable/ultimate-ai-agent clinpgx-database

For use in Claude.ai and ChatGPT

Download Skill