Can I perform batch lookups for multiple genes at once?

Yes, the skill includes a specific batch lookup workflow designed to handle multiple gene symbols or IDs while automatically managing API rate limits.

What is the difference between E-utilities and the Datasets API?

E-utilities is best for complex, cross-database searches, while the NCBI Datasets API is optimized for straightforward gene data and sequence retrieval.

Does this skill require an NCBI API key?

While optional, using a free NCBI API key is highly recommended to increase rate limits from 3 to 10 requests per second for more efficient data retrieval.

Can I search for genes associated with specific diseases?

Absolutely. You can use query patterns that combine gene symbols with phenotype or disease keywords to find relevant genetic associations.

Gene Database Integration

Name: Gene Database Integration
Author: Activer007

byActiver007

0•

Data Science & ML

Queries the NCBI Gene database to retrieve comprehensive genetic information, sequences, and functional annotations for biological research.

This skill empowers Claude to interact directly with the NCBI Gene database using both E-utilities and the modern Datasets API. It provides a robust framework for searching genes by symbol, name, or ID, and retrieving detailed metadata such as RefSeqs, chromosomal locations, and Gene Ontology (GO) annotations. Whether performing single lookups or high-throughput batch processing, this skill streamlines the process of gathering biological context, phenotypes, and disease associations, making it an essential tool for bioinformaticians, researchers, and life science developers.

Key Features

01Multiple output format support including JSON, XML, and FASTA

02High-efficiency batch processing with automated rate limit handling

030 GitHub stars

04Detailed metadata retrieval including GO terms, pathways, and RefSeqs

05Advanced gene search by symbol, ID, chromosome, or biological context

06Dual support for NCBI E-utilities and modern Datasets APIs

Use Cases

01Building automated pipelines for gene-disease association research

02Mapping gene symbols to stable NCBI IDs and reference sequences

03Annotating genomic datasets with functional information and phenotypes

What are Skills?·How to Install

Install with 🐟 Skill.Fish

npx skillfish add activer007/ordinary-claude-skills gene-database

For use in Claude.ai and ChatGPT

Download Skill