Performs NCBI BLAST sequence similarity searches using BioPython to identify homologous DNA or protein sequences.
This skill enables Claude to programmatically execute BLAST (Basic Local Alignment Search Tool) queries directly through BioPython. It supports a wide range of programs including blastn and blastp, allows for organism-specific filtering, and returns results in a structured JSON format. It is designed for researchers and bioinformaticians who need to automate sequence alignment, identify homologs, and retrieve genomic data without leaving their development environment.
Key Features
01Integration with BioPython for programmatic sequence analysis
020 GitHub stars
03Structured JSON output for easy data parsing and downstream processing
04Support for multiple BLAST programs including blastn, blastp, and tblastx
05Advanced filtering options by organism and E-value thresholds
06Support for both FASTA file inputs and raw sequence strings
Use Cases
01Automating sequence alignment tasks within a bioinformatics pipeline
02Identifying homologous genes or proteins across different species
03Verifying the identity of a DNA sequence against the NCBI database
