Can I use this for multi-channel pipetting?

Absolutely. It includes specific patterns for 8-channel and 96-channel operations, column-wise transfers, and optimizing tip usage for high-throughput plate operations.

What Opentrons hardware does this skill support?

This skill supports both the Flex and OT-2 robots, along with all official modules including the Thermocycler, Magnetic Module, Heater-Shaker, and Temperature Module.

Does it handle liquid tracking and labeling?

Yes, the skill includes patterns for defining liquid types with colors and descriptions, and loading specific volumes into wells for better visualization and tracking.

Does it support the latest Protocol API versions?

Yes, it is designed for Opentrons Python Protocol API v2 and provides patterns for current versions like 2.19, including requirements and metadata structures.

Can Claude help with PCR setup using this skill?

Yes, it provides logic for PCR setup, including reagent distribution, Thermocycler lid and block control, and executing complex cycling profiles.

Opentrons Lab Automation

Name: Opentrons Lab Automation
Author: lifangda

bylifangda

•

Productivity & Workflow

Automates laboratory liquid handling and experimental protocols for Opentrons Flex and OT-2 robots using Python Protocol API v2.

This skill provides specialized guidance for developing, simulating, and optimizing lab automation protocols on the Opentrons platform. It enables Claude to assist with complex pipetting workflows, hardware module management (thermocyclers, heaters, magnets), and deck layout configurations. By leveraging Protocol API v2 patterns, it helps scientists and engineers transition manual experiments into reproducible, automated code, ensuring best practices in liquid tracking, tip management, and protocol efficiency.

Key Features

01Python Protocol API v2 code generation and optimization

02Hardware module control (Thermocycler, Heater-Shaker, Magnetic, Temperature)

03Labware management and deck layout configuration

04Multi-channel pipette operations for high-throughput 96-well plate workflows

0516 GitHub stars

06Complex liquid handling patterns including serial dilutions and plate replication

Use Cases

01Developing serial dilution workflows with integrated mixing and tip tracking

02Automating high-throughput PCR preparation and thermocycler profile execution

03Coordinating hardware modules for temperature-sensitive enzymatic reactions and magnetic bead separation

What are Skills?·How to Install

Install with 🐟 Skill.Fish

npx skillfish add lifangda/claude-plugins opentrons-integration

For use in Claude.ai and ChatGPT

Download Skill