Which Opentrons API versions are supported?

This skill is optimized for Protocol API v2, specifically targeting the latest versions (up to v2.19) for both the OT-2 and Flex robots.

Can it help with protocol simulation?

Yes, it can implement simulation-aware logic using 'protocol.is_simulating()' to ensure your scripts are tested before running on the physical robot.

Can this skill handle multi-channel pipetting?

Yes, it provides patterns for 8-channel and 96-channel pipette operations, including row-wise and column-wise logic for 96-well plates.

Does it support hardware modules like Thermocyclers?

Absolutely. The skill includes comprehensive commands for controlling Thermocyclers, Heater-Shakers, Temperature Modules, and Magnetic Modules.

How does it handle labware and deck layouts?

The skill manages labware loading via API names, handles slot assignments (1-11 for OT-2, A1-D3 for Flex), and supports loading labware on adapters or modules.

Opentrons Lab Automation

Name: Opentrons Lab Automation
Author: ricable

byricable

•

Data Science & ML

Automates laboratory liquid handling workflows by generating and optimizing Opentrons Protocol API v2 scripts for Flex and OT-2 robots.

The Opentrons Integration skill empowers Claude to act as a laboratory automation engineer, specializing in the Python-based Opentrons Protocol API v2. It provides comprehensive support for designing automated pipetting workflows, configuring deck layouts, and controlling sophisticated hardware modules such as thermocyclers, heater-shakers, and magnetic blocks. By applying industry best practices for liquid tracking, flow rate optimization, and labware management, this skill helps scientists and developers transition from manual bench work to high-throughput, error-free robotic execution on both OT-2 and Flex platforms.

Key Features

01Generates Protocol API v2 compliant Python scripts for Flex and OT-2

021 GitHub stars

03Supports complex pipetting logic (Serial Dilutions, Plate Replication, PCR)

04Optimizes deck layouts and labware-on-adapter configurations

05Automates hardware module control (Thermocycler, Heater-Shaker, Magnetic)

06Implements liquid tracking, color coding, and flow rate management

Use Cases

01Designing complex serial dilution protocols for drug screening

02Implementing automated plate replication using multi-channel pipettes

03Automating high-throughput PCR plate preparation and thermocycling

What are Skills?·How to Install

Install with 🐟 Skill.Fish

npx skillfish add ricable/ultimate-ai-agent opentrons-integration

For use in Claude.ai and ChatGPT

Download Skill